3.亲水性AqT?接头：TFMP基团是高度疏水的，使用传统的乙烯和乙二醇型接头用TFMP标记的生物分子倾向于聚集并使标记的蛋白质不稳定。T2 A14 AqT?连接体通过将两个苏糖醇连接在一起制成，大大增加了sxLink?的亲水性及其水溶性（2.2 mg/mL饱和溶液）。该分子也具有更好的生物相容性，与其他生物分子的非特异性疏水相互作用降低，允许高载量的苯基二氮杂环丙烯基团。
2. Reversible disulfide for chemical crosslinking of any biomolecule containing a free thiol.
3. Hydrophilic AqT? linkers: TFMP group is highly hydrophobic, biomolecules labeled with a TFMP using a traditional ethylene and ethylene glycol-type linker tend to aggregate and destabilize the labeled protein. T2A14 AqT? linker is made by linking two threitols together, greatly increasing the hydrophilicity of sxLink? and its water solubility (2.2 mg/mL saturated solution). The molecule is also more biocompatible with decreased non-specific hydrophobic interactions with other biomolecules, allowing high loading of phenyldiazirine groups.
The product is sold as a lyophilized powder in either 1 vial of 250 ?g (Cat# CM81401-250UG) or 4 vials of 250 ?g (Cat# CM81401-4x250UG). One vial of dissolution buffer is included in each configuration.
